Elleaume H, Fiedler S, Estève F, Bertrand B, Charvet AM, Berkvens P, Berruyer G, Brochard T, Le Duc G, Nemoz C, Rénier R, Suortti P, Thomlinson W, Le Bas JF.

First Human transvenous coronary angiography at the European Synchrotron Radiation Facility

Physics in Medicine and Biology (2000); 45: L39-L43


Fiedler S, Elleaume H, Le Duc G, Nemoz C, Brochard T, Renier M, Bertrand B, Estève F, Le Bas JF, Suortti P, Thomlinson WC.

Dual energy coronary angiography in pigs using a Gd contrast agent

SPIE (2000); 3977: 1605-7422


Esteve F, Elleaume H, Bertrand B, Charvet AM, Fiedler S, Le Duc G, Corde S, Nemoz C, Renier M, Lefaix JL, Leplat JJ, Suortti P, Thomlinson W, Le Bas JF.

Coronary angiography with synchrotron X-ray source on pigs after iodine or gadolinium intravenous injection

Acad Radiol. 2002 May; 9 Suppl 1:S92-7


A. Peterzol, A. Bravin, P. Coan, H. Elleaume

Image Quality Evaluation of the acquisition system for intravenous coronary angiography at the European Synchrotron Radiation Facility"

Nuclear Instruments and Methods A 510 (2003) 45-50


A. Sarnelli, C. Nemoz, H. Elleaume, F. Estève, B. Bertrand, A. Bravin

Quantitative analysis of synchrotron radiation intravenous angiographic images

Physics in Medicine and Biology 50 (2005) 725-740


B. Bertrand, F. Estève, H. Elleaume, C. Némoz, S. Fiedler, A. Bravin, G. Berruyer, T. Brochard, M. Renier, J. Machecourt, W. Thomlinson, J. F. Le Bas

Comparison of synchrotron radiation angiography with conventional angiography for the diagnosis of in-stent restenosis after percutaneous transluminal coronary angioplasty

European Heart Journal, 2005 26: 1284-1291


E. Schultke, S. Fiedler, M. Kelly, K. Meguro, R. Griebel, B. Juurlink,G. LeDuc, F. Esteve, J.-F. Le Bas, M. Renier, C. Nemoz, K. Meguro

The potential for neurovascular intravenous angiography using K-edge digital subtraction angiography

Nuclear Instruments and Methods A 548 (2005) 84-87


S. Ohtsuka, K. Hyodo, W. Jin, T. Takeda, A. Maruhashi, I. Yamaguchi, M. Ando

Overview of clinical intravenous coronary angiography both in Japan and at ESRF

Nuclear Instruments and Methods A 548 (2005) 78-83


A. Peterzol, A. Bravin, P. Coan, H. Elleaume

Performance of the K-Edge Digital Subtraction Angiography imaging system at the European Synchrotron Radiation Facility

Radiation Protection Dosimetry 117(1-3): 44-9 (2006


A Sarnelli, H Elleaume, A Taibi, M Gambaccini and A.Bravin

K-edge digital subtraction imaging with dichromatic x-ray sources: SNR and dose studies

Physics in Medicine and Biology 51(17):4311-4328 (2006)


P. Baldelli, A Bravin, C. Di Maggio, G Gennaro, A.Sarnelli, A Taibi and M Gambaccini

Evaluation of the minimum iodine concentration for contrast enhanced subtraction mammography

Physics in Medicine and Biology 51(17):4233-51 (2006)


M. E Kelly, E. Schultke, S. Fiedler, C. Nemoz, R. Guzman, S. Corde, F. Esteve, G. LeDuc4, B. H J Juurlink and K Meguro

Synchrotron-based intravenous cerebral angiography in a small animal model

Phys. Med. Biol. 52 (2007) 1001–1012


A Sarnelli, A Taibi, P Baldelli, M Gambaccini and A Bravin

Quantitative analysis of the effect of energy separation in k-edge digital subtraction imaging

Phys. Med. Biol. 52 (2007) 3015–3026


P. Baldelli, A. Bravin, C. Di Maggio, G. Gennaro, M. Gambaccini, A. Sarnelli, A. Taibi

Evaluation of the minimum iodine concentration for contrast enhanced subtraction mammography

Nuc. Instr. Meth Physics Research A 580 (2007) 1115–1118

Phase contrast imaging



Moeckli R, Verdun FR, Fiedler S, Pachoud M, Schnyder P, Valley JF

Objective comparison of image quality and dose between conventional and synchrotron radiation mammography

Physics in Medicine and Biology 45 (12) 3509-23 (2000)


A. Bravin, S. Fiedler, W.C. Thomlinson

Very low dose mammography: new perspectives in Diffraction Enhanced Imaging (DEI) mammography

SPIE Vol. 4682, pp.167-173, 2002


E. Pagot, P. Cloetens, S. Fiedler, A. Bravin, P. Coan, J. Baruchel, J. Härtwig, W. Thomlinson,

A method to extract quantitative information from analyser-based X-ray phase contrast imaging

Applied Physics Letter, 82 (20), 3421-23 (2003)


A. Bravin,

Exploiting the X-ray refraction contrast with an analyser: the state of the art

Journal of Physics D: Applied Physics, 36, A-24-29 (2003)


S. Fiedler, E.Pagot, P. Cloetens, A. Bravin, J. Baruchel, J. Härtwig, P. Coan, B. Salicru, W. Thomlinson

Evaluation of Two Phase Contrast Techniques: Diffraction Enhanced Imaging and Propagation

SPIE Vol. 5030 (2003) 266-273


R. Moeckli, F. R. Verdun, S. Fiedler, M. Pachoud, S. Bulling, P. Schnyder, J.-F. Valley:

Influence of scatter reduction method and monochromatic beams on image quality and dose in mammography

Medical Physics, Vol. 30, No. 12 (2003)


S Fiedler, A Bravin, J Keyriläinen, M. Fernández, P Suortti, W Thomlinson, M Tenhunen, P Virkkunen and M-L Karjalainen-Lindsberg

Imaging lobular breast carcinoma: comparison of synchrotron radiation CT diffraction enhanced imaging technique with clinical CT, mammography and histology

Physics in Medicine and Biology 49 175-188 (2004)


J. Keyriläinen, M. Fernández, S. Fiedler, A. Bravin, M-L Karjalainen-Lindsberg, P. Virkkunen, E-M Elo, M. Tenhunen, P. Suortti, W. Thomlinson:

Visualisation of calcifications and thin collagen strands in human breast tumour specimens by the diffraction-enhanced imaging technique: a comparison with conventional mammography and histology

European Journal of Radiology, , 53, 226-237 (2005)


M. Fernández, J. Keyriläinen, M.-L. Karjalainen-Lindsberg, M. Leidenius, K. von Smitten d, S. Fiedler and P. Suortti

Human breast tissue characterisation with small-angle X-ray scattering

Spectroscopy 18 (2004) 167–176


P. Coan, S. Fiedler, E. Pagot, P. Cloetens, J. Baruchel, A. Bravin

Phase contrast X-ray imaging combining free space propagation and Bragg diffraction

J. Synchrotron Radiation, 12 (2005) 241-245


E. Pagot, S. Fiedler, P. Cloetens, A. Bravin, P. Coan, K. Fezzaa, J. Baruchel, J. Härtwig

Quantitative comparison between two-phase contrast techniques: Diffraction Enhanced Imaging and Phase Propagation Imaging

Phys Med. Biol. 50 (2005) 709-724


A. Wagner, M. Aurich, M. Stoessel, N. Sieber, W-D Wetzel, J. Mollenhauer, K. Schmuck, C. Muehleman, M. Lohmann, B. Reime, J. Metge, P. Coan, A. Bravin, F. Arfelli, L. Rigon, R.-H Menk

Chance and limit of imaging of articular cartilage in vitro in healthy and arthritic joints - DEI (Diffraction Enhanced Imaging) in comparison with MRI, CT and ultrasound

SPIE Vol. 5746 (2005) 542-549


M. Fernandez, J. Keyrilainen, R. Serimaa, M. Torkkeli, M.-L. Karjalainen-Lindsberg, M. Leidenius, K. von Smitten, M. Tenhunen, S. Fiedler, A. Bravin, T. M. Weiss and P. Suortti

Human Breast Cancer in vitro: Matching Histo-pathology with Small-angle X-ray Scattering and Diffraction Enhanced X-Ray Imaging

Phys. Med. Biol. 50 (2005) 2991–3006


J. Schlüter, M. Lohmann, J.Metge, B. Reime

Diffraction Enhanced Imaging: a new X-ray method for detecting internal pearl structures

Journal of Gemmology, 29 (2005) 7/8 401-406


A Wagner, M Aurich, N Sieber, M Stoessel, W-D Wetzel, K Schmuck , M Lohmann, J Metge, B Reime, P Coan, A Bravin, F Arvelli, G Heitner, R Menk, T Irving, Z Zhong, C Muehleman, J A. Mollenhauer

Options and Limitations of Joint Cartilage Imaging: DEI in Comparison to MRI and Sonography

Nuclear Instruments and Methods A 548 (2005) 47–53


Wagner A, Sachse A, Keller M, Wagner O, Aurich M, Wetzel W-D, Venbrocks RA, Wiederanders B, Hortschansky P, Horn J, Schmuck K, Lohmann M, Reime B, Metge J, Arfelli F, Menk R, Rigon L, Muehleman C, Bravin A, Coan P Mollenhauer J

Evaluation of Titanium Implant Ingrowth into Bone by Diffraction Enhanced Imaging (DEI)

Physics in Medicine and Biology 51 (2006) 1313-1324


E. Pagot, S. Fiedler, P.Cloetens, A. Bravin, P. Coan, K. Fezzaa, J. Baruchel, J. Härtwig

Corrigendum: Quantitative comparison between two-phase contrast techniques: Diffraction Enhanced Imaging and Phase Propagation Imaging

Phys. Med. Biol. 51 (2006) 1957-1957


Ya. I. Nesterets, P. Coan, T. E. Gureyev, A. Bravin, P. Cloetens and S. W. Wilkins

On qualitative and quantitative analysis in analyser-based imaging

Acta Crystallographica Section A (2006) A62, 296–308


U.Bottigli B.Golosio, G.L. Masala, P.Oliva, S.Stumbo, A. Bravin, A. Bacci , L.Serafini, C. Maroli , V. Petrillo, M. Ferrario, C. Vaccarezza

Effect of Different Spectral Distributions to Image a Contrast Detail Phantom in the Mammography Energy Range

Nuovo Cimento C 29 (2): 215-228 (2006)


A. Bravin, J. Keyriläinen, M. Fernandez, S. Fiedler, C. Nemoz, M-L Karjalainen-Lindsberg, M. Tenhunen, P. Virkkunen, M. Leidenius, K. von Smitten, P. Sipila and P. Suortti

High-resolution CT by diffraction enhanced x-ray imaging: mapping of breast tissue samples and comparison with their histo-pathology

Phys. Med. Biol. 52 (8) 2197–2211 (2007)


A. Bravin, V. Mocella, P. Coan, A. Astolfo, and C. Ferrero

A numerical wave-optical approach for the simulation of analyzer-based x-ray imaging

Optics Express Vol. 15, No. 9, 5641-5648 (2007)


Paola Coan and Alberto Bravin

Analysis of the x-ray refraction using an array-structured detector



H. Suhonen, M. Fernandez, A. Bravin, J. Keyriläinen and P. Suortti

Refraction and scattering of X-rays in analyzer based imaging

J. Synchrotron Radiation, 14 (2007) 512-521


F Pfeiffer, O Bunk, C David, M Bech, G Le Duc, A Bravin and P Cloetens

High-resolution brain tumor visualization using three-dimensional x-ray phase contrast tomography

Phys. Med. Biol. 52 (2007) 6923–6930

J Keyriläinen, M Fernández, M-L Karjalainen-Lindsberg, P Virkkunen, M Leidenius, K von Smitten, P Sipilä, S Fiedler, H Suhonen, P Suortti, A Bravin

Towards high-contrast breast CT at low radiation dose

Radiology, 2008: 249 (1) 321-327

T. Schneider, P. Coan, D. Habs, M. Reiser

Einsatz brillanter Röntgenstrahlen in der Mammographie Entwicklungen und Perspektiven von Phasenkontrasttechniken

Radiologe 2008 48: 345–350

De Felici M, Felici R, Ferrero C, Tartari A, Gambaccini M, Finet S

Structural characterization of the human cerebral myelin sheath by small angle x-ray scattering.

Phys. Med. Biol. 53 (2008) 5675–5688

F. Pfeiffer, C. David, O. Bunk, T. Donath, M. Bech, G. Le Duc, A. Bravin, and P. Cloetens

Region-of-Interest Tomography for Grating-Based X-Ray Differential Phase-Contrast Imaging

Phys. Rev. Lett. 101, 168101 (2008)

Fernández M, Suhonen H, Keyriläinen J, Bravin A, Fiedler S, Karjalainen-Lindsberg ML, Leidenius M, von Smitten K, Suortti P.

USAXS and SAXS from cancer-bearing breast tissue samples

Eur J Radiol. 68S (2008) S89-S94

Coan P, Mollenhauer J, Wagner A, Muehleman C, Bravin A.

Analyzer-based imaging technique in tomography of cartilage and metal implants: A study at the ESRF

Eur J Radiol. 68S (2008) S41-S48

P. Coan, F. Gruener, C. Glaser, T. Schneider, A. Bravin, M. Reiser, D. Habs

Phase contrast medical imaging with compact X-ray sources at the Munich-Centre for Advance Photonics (MAP)

Nuclear Instruments and Methods A 608 (2009) S44–S46



Bayat S, Le Duc G, Porra L, Berruyer G, Nemoz C, Monfraix S, Fiedler S, Thomlinson W, Suortti P, Standertskjöld-Nordenstam CG, Sovijärvi ARA.

Quantitative functional lung imaging with synchrotron radiation using inhaled xenon as contrast agent

Physics in Medicine and Biology (2001) 46 (12): 3287-3299.


Porra L, Monfraix S, Berruyer G, Le Duc G, Nemoz C, Thomlinson W, Suortti P, Sovijarvi AR, Bayat S.

Effect of tidal volume on distribution of ventilation assessed by synchrotron radiation CT in rabbit

Journal Applied Physiology (2004) Feb 13


S Monfraix, S Bayat, L Porra, G Berruyer, Christian Nemoz, W Thomlinson, P Suortti and A R A Sovijarvi

Quantitative measurement of regional lung gas volume by synchrotron radiation computed tomography

Physics in Medicine and Biology (2005) 50 (1): 1-11


Sam Bayat, Liisa Porra, Heikki Suhonen, Christian Nemoz, Pekka Suortti, and Anssi R.A. Sovijarvi

Differences in the time course of proximal and distal airway response to inhalated histamine studied by synchrotron radiation CT

Journal Applied Physiology doi:10.1152/japplphysiol.00594.2005


Suhonen H, Porra L, Bayat S, Sovijärvi ARA and Suortti P.

Simultaneous in vivo synchrotron radiation computed tomography of regional ventilation and blood volume in rabbit lung using combined k-edge and temporal subtraction.
Phys Med Biol 2008 53: 775-791.

Sovijärvi ARA, Porra L, and Suortti P.

Uusi keuhkojen toimintahäiriöiden tutkimismenetelmä –synkrotroni-ksenon-kuvantaminen (KES).
DUODECIM Medical Journal 2008; 124(3): 271-8 (in Finnish).

Bayat S, Porra L, Suhonen H, Janosi T, Strengell S, Habre W, Petak F, Hantos Z, Suortti P, Sovijärvi A.

Imaging of lung function using synchrotron radiation computed tomography: What's new?
Eur J Radiol. 68S (2008) S78-S83

Bayat S, Porra L, Suhonen H, Suortti P and Sovijärvi ARA.

Paradoxical conducting airway response and heterogeneous regional ventilation after histamine inhalation in healthy anaesthetized rabbits studied by synchrotron radiation CT.
J Appl Physiol 2009; 106: 1949–1958.

Bayat S, Strengell S, Porra L, Janosi TZ, Petak F, Suhonen H, Suortti P, Hantos Z, Sovijärvi AR, Habre W.

Methacholine and Ovalbumin Challenges Assessed by Forced Oscillations and Synchrotron Lung Imaging.
Am J Respir Crit Care Med. 2009 May 29.

Adam JF, Bayat S, Porra L, Elleaume H, Esteve F, Suortti P

Quantitative functional imaging and kinetic studies with high-Z contrast agents using synchtrotron radiation computed tomography
Clinical and experimental pharmacologogy and physiology 2009, 36 (1) 95-106


Computed Tomography and Brain Vasculature studies

Le Duc G, Corde S, Elleaume H, Estève F, Charvet AM, Brochard T, Fiedler S, Collomb A, Le Bas JF .

Feasibility of synchrotron radiation computed tomography on rats bearing glioma after iodine or gadolinium injection”.

European Radiology (2000); 10(9): 1487-1492


Adam JF, Elleaume H, Le Duc G, Corde S, Charvet AM, Troprès I, Le Bas JF, Estève F.

Absolute cerebral blood volume and blood flow measurements based on synchrotron radiation quantitative computed tomography”.

Journal of Cerebral Blood Flow and Metabolism (2003); 23:499-512


Le Duc G, Corde S, Charvet AM, Elleaume H, Farion R, Le Bas JF, Estève F.

In vivo measurement of Gd concentration in a rat glioma model by monochromatic quantitative CT: comparison between Magnevist® and Gadovist®.”

Investigative Radiology 39 (7):385-93(2004)


Jean-François Adam, Christian Nemoz, Alberto Bravin, Stefan Fiedler, Sam Bayat, Sylvie Monfraix, Gilles Berruyer, Anne Marie Charvet, Jean-François Le Bas, Hélène Elleaume, François Estève

High-resolution blood-brain barrier permeability and blood volume imaging using quantitative synchrotron radiation computed tomography: a feasibility study on the F98 rat brain glioma

Journal of Cerebral Blood Flow and Metabolism, (2005) 25, 145-153


J. Segers, G. Le Duc, C. Laumonier, I. Tropres, L Vander Elst, Rt N. Muller

Evaluation of Gd-EOB-DTPA Uptake in a Perfused and Isolated Mouse Liver Model. Correlation Between Magnetic Resonance Imaging and Monochromatic Quantitative Computed Tomography

Investigative Radiology 40,(9), September 2005, 574-582

Risser L, Plouraboué F, Steyer A, Cloetens P, Le Duc G, Fonta C.

From homogeneous to fractal normal and tumorous micro-vascular networks in the brain.

Journal of Cerebral Blood Flow and Metabolism 2006, doi:10.1038/sj.jcbfm.9600332


Alric C.,Serduc R.,Mandon C.,Taleb J.,Le Duc G.,Le Meur-Herland A.,Billotey C.,Perriat P.,Roux S.,Tillement O. 

Gold nanoparticles designed for combining dual modality imaging and radiotherapy
Gold Bulletin 41, 90-97 (2008)

C Alric, J Taleb, G Le Duc, C Mandon, C Billotey, A Le Meur-Herland, T Brochard, F Vocanson, M Janier, P Perriat, S Roux,, and O Tillement

Gadolinium Chelate Coated Gold Nanoparticles As Contrast Agents for Both X-ray Computed Tomography and Magnetic Resonance Imaging
Journal American Chemical Society 2008, 130, 5908–5915

D Balvay, I Tropres, R Billet, A Joubert, M Peoc’h, C A. Cuenod, G Le Duc,

Mapping the Zonal Organization of Tumor Perfusion and Permeability in a Rat Glioma Model by Using Dynamic Contrast-enhanced Synchrotron Radiation CT
Radiology 2009, Vol. 250, 3, 692-702

C Ricard, M. Fernandez, J. Gastaldo, L. Dupin, L. Somveille, R. Farion, H. Requardt, J.-C. Vial, H. Elleaume, C. Segebarth, and B. van der Sanden

Short-term effects of synchrotron irradiation on vasculature and tissue in healthy mouse brain
Journal of Synchrotron Radiation 2009 (16) 477-483


Microbeam Radiation Therapy and Microdosimetry


Schweizer PM, Spanne P, Di Michiel M, Jauch U, Blattmann H, Laissue JA

Tissue lesions caused by microplanar beams of synchrotron-generated X-rays in Drosophila melanogaster”

Internation Journal of Radiation Biology 76 (4): 567-574 2000


Stepanek, J Blattmann, H Laissue, JA Lyubimova, N Di, Michiel M Slatkin, DN

Physics study of microbeam radiation therapy with PSI-version of Monte Carlo code GEANT as a new computational tool”

Medical Physics 27 7 1664-75 (2000)


Laissue JA, Blattmann H, Di Michiel M, Slatkin DN, Lyubimova N, Guzman R, Werner Zimmermann W, Jaggy A, Smilowitz HM, Stettler R, Kircher P, Bley T, Brauer E, Stepanek J, Bravin A, Renier R, Le Duc G, Nemoz C, Thomlinson WC, Wagner HP.

The weanling piglet cerebellum: a surrogate for tolerance to MRT (Microbeam Radiation Therapy) in pediatric neuro-oncology.

SPIE, (2001) 4508: 65-73


A.B. Rosenfeld, M. Lerch, T. Kron, E. Bräuer-Krisch, A. Bravin et al.

Feasibility study of online high-spatial-resolution MOSFET dosimetry in static and pulsed x-ray radiation fields"

IEEE Transactions on Nuclear Science, 48 (6), pp.2061 -2068, 2001


E. Bräuer-Krisch, A. Bravin, M. Lerch et al.

MOSFET Dosimetry for Microbeam Radiation Therapy at the European Synchrotron Radiation Facility"

Medical Physics, 30 (4) 583-589, 2003


Joneja O.P., Negreanu C., Stepanek J., Chawla R.

Comparison of Monte Carlo simulations of photon/electron dosimetry in microscale applications"

Australas Phys Eng Sci Med. 2003 Jun;26(2):63-9


E. Bräuer-Krisch, A. Bravin, L. Zhang, J. Stepanek, H. Blattmann, D. N. Slatkin, J.-O. Gebbers, M. Jasmin, J.A. Laissue:

Characterization of a tungsten/gas multislit collimator (TMSC) for microbeam radiation therapy at the European Synchrotron Radiation Facility"

Rev. Scient. Instruments 76, 064303 1-7 (2005) + Erratum 77,039901-1 , 2006


E Bräuer-Krisch, H Requardt, P Regnard, S Corde, E Siegbahn,G LeDuc, T Brochard, H Blattmann, J Laissue and A Bravin

New irradiation geometry for microbeam radiation therapy (MRT)

Phys. Med. Biol. 50 (2005) 3103-3111


H. Blattmann, J.-O.Gebbers, E. Brauer, A. Bravin, G. Le Duc, W. Burkard, M. Di Michiel, V. Djonov, D. N. Slatkin, J. Stepanek, J. A. Laissue

Applications of synchrotron x-rays for radiotherapy.

Nuclear Instruments and Methods, A 548 (2005) 17–22


E. Brauer-Krisch, H. Requard, P. Regnard, S. Corde, E. Siegbahn, G. LeDuc, H. Blattmann, J. Laissue, J. Stepanek, A. Bravin

Exploiting geometrical irradiation possibilities in MRT application, Submitted

Nuclear Instruments and Methods, A 548 (2005) 69–71


E.A. Siegbahn, E. Brauer-Krisch, J. Stepanek, H. Blattmann, J.A. Laissue, A. Bravin

Dosimetric studies of microbeam radiation therapy with Monte Carlo simulations

Nuclear Instruments and Methods, A 548 (2005) 54–58


M. De Felici, A. Bravin, R. Felici, C. Ferrero, S. Finet, M. Gambaccini, A. Taibi, A. Tartari

Effects induced by the fine structure of biological tissues on microbeam dose deposition: a numerical study

Nuclear Instruments and Methods, A 548 (2005) 59–64


M. Miura, H. Blattmann, E. Brauer-Krisch, A. Bravin, A.L. Hanson, M.M. Nawrocky, P.L. Micca, D.N Slatkin, J.A. Laissue

Radiosurgical palliation of aggressive murine SCCVII squamous cell carcinomas using synchrotron-generated X-ray microbeams

British Journal of Radiology 2006 79 (937) 71-75


B. Rosenfeld, E.A. Siegbahn, E. Bräuer-Krisch, A. Holmes-Siedle, M.L.F. Lerch, A. Bravin, I.M. Cornelius, G. Takacs, N. Painuly and T. Kron

Edge on Face-to-Face paired (EOFFP) MOSFETs for Synchrotron Microbeam Dosimetry: MC modelling

Accepted by IEEE Transaction on Nuclear Science


R. Serduc, P. Vérant, J-C Vial, R. Farion, L. Rocas, C. Rémy, T. Fadlallah, E. Brauer, A. Bravin, J. Laissue, H. Blattmann, and B. van der Sanden

In vivo two-photon microscopy study of short-term effects on normal mouse brain microvasculature after microbeam irradiation.

International Journal of Radiation Oncology, Biology,Physics Vol.64, 5, 1519-1527 (2006)


H. M. Smilowitz, H. Blattmann, E. Bräuer-Krisch, A. Bravin, M. Di Michiel, J.-O. Gebbers, A. L. Hanson, N. Lyubimova, D. N. Slatkin§, J. Stepanek, and J. A. Laissue

Synergy of Gene-Mediated Immunoprophylaxis and Unidirectional Microbeam Radiation Therapy for Advanced Intracerebral Rat 9L Gliosarcomas

J. of Neuro-oncology 78: 135–143 (2006)


E. Bräuer-Krisch, A. Bravin, L. Zhang, E. Siegbahn, J. Stepanek, H. Blattmann, D. N. Slatkin, J.-O. Gebbers, M. Jasmin, J.A. Laissue

Erratum: Characterization of a tungsten/gas multislit collimator (TMSC) for microbeam radiation therapy at the European Synchrotron Radiation Facility [Rev. Sci. Instrum. 76, 064303 (2005)]

Rev. Scient. Instruments 77, 039901 1 (2006)


E. A. Siegbahn, J. Stepanek, E. Bräuer-Krisch, A. Bravin

Determination of dosimetrical quantities used in microbeam radiation therapy (MRT) with Monte Carlo simulations

Medical Physics 33 (9) 3248-3259 (2006)


J. Spiga, E. A. Siegbahn, E. Bräuer-Krisch, P. Randaccio, and A. Bravin

Microdosimetry for Microbeam Radiation Therapy (MRT): theoretical calculations using the Monte Carlo toolkit

IEEE Conference Proceedings , Medical Imaging Conference, San Diego, 2006.


M. De Felici, R. Felici, C. Ferrero, A. Bravin, A. Tartari, M. Gambaccini

Monte Carlo assessment of peak-to-valley dose ratio for MRT

Nuclear Instruments and Methods in Physics Research A 580 (2007) 489–492


J. Spiga, E. A. Siegbahn, E. Bräuer-Krisch, P. Randaccio, A. Bravin

The GEANT4 toolkit for microdosimetry calculations: Application to microbeam radiation therapy “MRT”

Medical Physics 34 (11) 4322-4330 (2007)


Laissue JA, Blattmann H, Wagner HP, Grotzer MA, Slatkin DN

Prospects for microbeam radiation therapy of brain tumours in children to reduce neurological sequelae

Developmental Medicine and Child Neurology (2007) 49 (8): 577-581


P Regnard, G Le Duc, E Bräuer-Krisch, I Tropres, E A Siegbahn, A Kusak, C Clair, H Bernard, D Dallery, J A Laissue and A Bravin

Irradiation of intracerebral 9L gliosarcoma by a single array of microplanar x-ray beams from a synchrotron: balance between curing and sparing

Phys. Med. Biol. 53 (2008) 861–878


R Serduc, Y van de Looij, G Francony, O Verdonck, B van der Sanden, J A Laissue, R Farion, E Bräuer-Krisch, E Siegbahn, A Bravin, Y Prezado, C Segebarth, C Rémy and H Lahrech

Characterization and quantification of cerebral edema induced by synchrotron x-ray microbeam radiation therapy

Phys. Med. Biol. 53 (2008) 1153-1166

Vérant P, Serduc R, van der Sanden B, Chantal R, Ricard C, Coles JA, Vial JC.

 Subtraction method for intravital two-photon microscopy: intraparenchymal imaging and quantification of extravasation in mouse brain cortex.

J Biomed Opt. 2008 Jan-Feb;13(1):011002.

R Serduc, T Christen, J Laissue, R Farion, A Bouchet, B van der Sanden, C Segebarth, E Bräuer-Krisch, G Le Duc, A Bravin, C Remy and E L Barbier

 Brain tumor vessel response to synchrotron microbeam radiation therapy: a short-term in vivo study

Phys. Med. Biol. 53 (2008) 3609–3622


Schültke E., Juurlink B.H., Ataelmannan K., Laissue J., Blattmann H., Brauer-Krisch E., Bravin A., Minczewska J., Crosbie J., Taherian H., Frangou E., Wysokinsky T., Chapman L.D., Griebel R., Fourney D.

Memory and survival after microbeam radiation therapy

European Journal of Radiology 68S (2008) S142-S146


De Felici M., Siegbahn E.A., Spiga J., Hanson A.L., Felici R., Ferrero C., Tartari A., Gambaccini M., Keyriläinen J., Brauer-Krisch E., Randaccio P., Bravin A.

 Monte Carlo code comparison of dose delivery prediction for Microbeam Radiation Therapy

Journal of Physics : Conference Series 102, 012005-1-012005-6 (2008)

Régnard P, Bräuer-Krisch E, Troprès I, Keyriläinen J, Bravin A, Le Duc G.

 Enhancement of survival of 9L gliosarcoma bearing rats following intracerebral delivery of drugs in combination with microbeam radiation therapy.

European Journal of Radiology 68S (2008) S151-S155

 E. A. Siegbahn, E. Bräuer-Krisch, A. Bravin, H. Nettelbeck, M. L. F. Lerch, and A. B. Rosenfeld

 MOSFET dosimetry with high spatial resolution in intense synchrotron-generated x-ray microbeams

Medical Physics (2009) 36, 4, 1128-1137

Y. Prezado, M. Renier and A. Bravin

 A new method of creating minibeam patterns for synchrotron radiation therapy: a feasibility study

J. Synchrotron Rad. (2009). 16, 582–586

R. Serduc, E. Brauer-Krisch, A. Bouchet, L. Renaud, Th. Brochard, A. Bravin, J. A. Laissue and G. Le Duc

 First trial of spatial and temporal fractionations of the delivered dose using synchrotron microbeam radiation therapy

J. Synchrotron Rad. (2009). 16, 587–590

 Bräuer-Krisch E, Requardt H, Brochard T, Berruyer G, Renier M, Laissue JA, Bravin A.

 New technology enables high precision multislit collimators for microbeam radiation therapy

Rev Sci Instrum. 2009 Jul;80(7):074301.

Prezado Y, Fois G, Le Duc G, Bravin A.

 Gadolinium dose enhancement studies in microbeam radiation therapy.

Med Phys. 2009 Aug;36(8):3568-74.

R. Serduc, A. Bouchet, E. Bräuer-Krisch, J.A. Laissue, J. Spiga, S. Sarun, A. Bravin, C. Fonta, L. Renaud, J. Boutonnat, E. A. Siegbahn, F. Esteve and G. Le Duc

 Synchrotron microbeam radiation therapy for rat brain tumor palliation—influence of the microbeam width at constant valley dose

Phys. Med. Biol. 54 (2009) 6711–6724


Computed Tomography Therapy and Photon Activation Therapy


S. Corde, M.C. Biston, H. Elleaume, F. Esteve, A.M. Charvet, A. Joubert, V. Ducros, S. Bohic, A. Simionovici, T. Brochard, C. Nemoz, M. Renier, I. Troprez, S. Fiedler, A. Bravin, W. Thomlinson, J. F. Le Bas and J. Balosso.

Lack of cell death enhancement after irradiation by monochromatic synchrotron X-ray at the K-shell edge of platinum incorporated in living SQ20B human cells as cis-diamminedichloroplatinum (II)”

Radiation Research, 158, 763-770 (2002)


Esteve F, Corde S, Elleaume H, Adam JF, Joubert A, Charvet AM, Biston MC, Balosso J, Le Bas JF

Enhanced radio sensitivity with iodinated contrast agents using monochromatic synchrotron X-rays on human cancerous cells”

Acad Radiol. 2002 Aug; 9 Suppl 2: S540-3.


 S. Corde, J. Balosso, H. Elleaume, M. Renier , A. Joubert, M.C. Biston, J.F. Adam, A. M. Charvet, T. Brochard, JF Le Bas, F. Estève, N. Foray.

Synchrotron photoactivation of cis-platin (PAT-Plat) elicits an extra-number of DNA breaks that stimulate RAD51-mediated repair pathways”

Cancer Research, 63, 3221-3227 (2003)


Adam JF, Elleaume H, Joubert A, Biston MC, Charvet AM, Balosso J, Le Bas JF, Estève F

Synchrotron Radiation therapy of malignant brain glioma loaded with an iodinated contrast agent: First trial on rats bearing F98 gliomas.

International Journal of Radiation Oncology Biology Physics (2003) 57(5): 1413-26


Biston MC et al.

Cure of Fisher rats bearing radio resistant F98 glioma treated with cis-platinum and irradiated with monochromatic synchrotron X-rays”

Cancer Research, 64, 2317-2323 (2004)


Corde S, Joubert A, JF Adam, Charvet AM, Le Bas JF, Esteve F, Elleaume H, Balosso J

Synchrotron radiation-based experimental determination of the optimal energy for cell radiotoxicity enhancement following photoelectric effect on stable iodinated compounds

British Journal of Cancer (2004) 91, 544 – 551


Boudou C, Biston MC, Corde S, Adam JF, Ferrero C, Esteve F, Elleaume H.

Synchrotron stereotactic radiotherapy: dosimetry by Fricke gel and Monte Carlo simulations.

Phys Med Biol. 2004 Nov 21;49(22):5135-44.


C Boudou, M C Biston, J F Adam, A Joubert, S Corde, A M Charvet, F Estève and H Elleaume

Fricke dosimetry for synchrotron stereotactic radiotherapy

J. Phys.: Conf. Ser. 3 (2004), p. 209-212


 Adam JF, Biston MC, Joubert A, Charvet AM, Le Bas JF, Esteve F, Elleaume H.

Enhanced delivery of iodine for synchrotron stereotactic radiotherapy by means of intracarotid injection and blood-brain barrier disruption: Quantitative iodine biodistribution studies and associated dosimetry.

Int J Radiat Oncol Biol Phys. 2005 Mar 15;61(4):1173-82


C. Boudou, M.-C. Biston, S. Corde, J.-F. Adam, A. Joubert, A.-M. Charvet, C. Nemoz, C. Ferrero, F. Esteve, H. Elleaume

Dosimetry for synchrotron stereotactic radiotherapy: Fricke gel and Monte Carlo calculations

Nuclear Instruments and Methods, in Physics Research Section A: Accelerators, Spectrometers, Detectors and Associated Equipment, 2005, 548(1-2): p. 65-68.


 A Joubert, M-C Biston, C Boudou, J-L Ravanat, T Brochard, A-M Charvet, F Estève, J Balosso, N Foray

Irradiation in presence of iodinated contrast agent: results in radiosensitization of endothelial cells: consequences for CT therapy

Int. J. Radiation Oncology Biol. Phys., Vol. 62, No. 5, pp. 1486–1496, 2005


Foray, N, Charvet, AM, Duchemin, D, Favaudon, V, and Lavalette, D.,

The repair-rate of radiation-induced DNA damage: A stochastic interpretation based on Gamma function.

Journal of Theoretical Biology Oct 21;236(4):448-58, 2005


Boudou C., Balosso J., Estève F., and Elleaume H.

Monte Carlo dosimetry for synchrotron stereotactic radiotherapy of brain tumours

Physics in Medicine and Biology, 2005, 50(20): p. 4841-51


J-F Adam, A Joubert, M-C Biston, A-M Charvet, M Peoc'h, J-F Le Bas, J Balosso, F Esteve, and H Elleaume

Prolonged survival of Fischer rats bearing F98 glioma after iodine-enhanced synchrotron stereotactic radiotherapy

Int. J. of Radiation Oncology Biol. Physics Vol. 64, No. 2, pp. 603–611, 2006


Z Bencokova, L. Pauron, C. Devic, A. Joubert, J. Gastaldo, C. Massart, J. Balosso, N. Foray

Molecular and cellular response of the most extensively used rodent glioma models to radiation and/or cisplatin

J Neurooncol, DOI 10.1007/s11060-007-9433-0


J. Rousseau, C. Boudou, R. F. Barth, J. Balosso, F. Esteve and H. Elleaume

Enhanced Survival and Cure of F98 Glioma Bearing Rats following Intracerebral Delivery of Carboplatin in Combination with Photon Irradiation

Clin Cancer Res 2007;5195 13(17) September 1, 2007


N. Freud, J. M. Letang, C. Mary, C. Boudou, C. Ferrero, H. Elleaume, A. Bravin, F. Esteve, and D. Babot

Fast Dose Calculation for Stereotactic Synchrotron Radiotherapy

Conf Proc IEEE Eng Med Biol Soc. 2007;1:3914-7.


 Boudou C, Tropres I, Rousseau J, Lamalle L, Adam JF, Esteve F, Elleaume H

Polymer gel dosimetry for synchrotron stereotactic radiotherapy and iodine dose-enhancement measurements

Phys Med Biol. (2007) 52 (16) 4881-4892


 Gastaldo J, Viau M, Bencokova Z, Joubert A, Charvet AM, Balosso J, Foray N

Lead contamination results in late and slowly repairable DNA double-strand breaks and impacts upon the ATM-dependent signaling pathways

Toxicology Letters (2007) 173 (3): 201-214


 Bencokova Z, Pauron L, Devic C, Joubert A, Gastaldo J, Massart C, Balosso J, Foray N

Molecular and cellular response of the most extensively used rodent glioma models to radiation and/or cisplatin

Journal of Neuro-oncology (2008) 86 (1): 13-21


 Renier W, Joubert A, Bencokova Z, Gastaldo J, Massart C, Foray N

Consequences of the bleed-through phenomenon in immunofluorescence of proteins forming radiation-induced nuclear foci

Int. J. of Radiation Biology (2007) 83 (8): 543-549


Bencokova Z, Pauron L, Devic C, Joubert A, Gastaldo J, Massart C, Balosso J, Foray N “Molecular and cellular response of the most extensively used rodent glioma models to radiation and/or cisplatin”
Journal of Neuro-oncology (2008) 86 (1): 13-21

N Freud, J M Létang, C Mary, C Boudou, C Ferrero, H Elleaume, A Bravin, F Estève, and D Babot ”A Hybrid Approach for Fast Simulation of Dose Deposition in Stereotactic Synchrotron Radiotherapy”

J.F. Adam, M.C. Biston, J. Rousseau, C. Boudou, A.M. Charvet, J. Balosso, F. Esteve, H. Elleaume ”Heavy element enhanced synchrotron stereotactic radiotherapy as a promising brain tumour treatment”
Physica Medica (2008) 24, 92-97

Fioravanti E.,Durá M.A.,Lascoux D.,Micossi E.,Franzetti B.,McSweeney S. - Structure of the stress response protein DR1199 from Deinococcus radiodurans: A member of the DJ-1 superfamily
Biochemistry 47, 11581-11589 (2008)

J. Gastaldo, C. Boudou, L. Lamalle, I Tropres, S. Corde, A. Sollier, G. Rucka, H. Elleaume ”Normoxic polyacrylamide gel doped with iodine: Response versus X-ray energy”
European Journal of Radiology 68S (2008) S118-S120

J. Rousseau, R. F. Barth, M. L. Moeschberger, and H. Elleaume ”Efficacy of intracerebral delivery of carboplatin in combination with photon irradiation for treatment of F98 glioma-bearing rats”
Int. J. Radiation Oncology Biol. Phys., Vol. 73, No. 2, pp. 530–536, 2009

Y. Prezado, G. Fois, M. Edouard, C. Nemoz, M. Renier, H. Requardt, F. Estève, J. F. Adam, H. Elleaume, A. Bravin ”Biological equivalent dose studies for dose escalation in the stereotactic synchrotron radiation therapy clinical trials”
Med. Phys. Volume 36, Issue 3, pp. 725-733 (March 2009)

J. Rousseau, J.-F. Adam, P. Deman, T.-D. Wu, J.-L. Guerquin-Kern, B. Gouget, R. F. Barth, F. Esteve, and H. Elleaume ”Intracerebral delivery of 5-iodo-20-deoxyuridine in combination with synchrotron stereotactic radiation for the therapy of the F98 glioma”
Journal of Synchrotron Radiation 2009 (16) 573-581

Smekens F, Freud N, Létang JM, Adam JF, Ferrero C, Elleaume H, Bravin A, Estève F, Babot D. ”Simulation of dose deposition in stereotactic synchrotron radiation therapy: a fast approach combining Monte Carlo and deterministic algorithms.”
Phys Med Biol. 2009 Aug 7;54(15):4671-85.

Biston MC, Joubert A, Charvet AM, Balosso J, Foray N. “In Vitro and In Vivo Optimization of an Anti-glioma Modality Based on Synchrotron X-Ray Photoactivation of Platinated Drugs.”
Radiation Research, 2009 Sep;172(3):348-58





Elleaume H, Charvet AM, Le Duc G, Estève F, Bertrand B, Corde S, Farion R, Lefaix JL, Leplat JJ, Berkvens P, Berruyer G, Brochard T, Dabin Y, Draperi A, Fiedler S, Nemoz C, Perez M, Rénier M, Suortti P, Thomlinson W, Le Bas JF.

In vivo K-edge imaging with synchrotron radiation.

Cellular and Molecular Biology 46 (6): 1065-1075 (2000)



Moeckli R, Verdun FR, Fiedler S, Pachoud M, Hessler C, Meuli R, Valley JF

Assessment of the image contrast improvement and dose reduction in mammography with synchrotron radiation compared to standard units”

Nucl. Inst. and Meth. A, 467-468 1349-1352 (2001)



H. Elleaume, A.M. Charvet, S. Corde, F. Estève, J.F. Le Bas.

Performance of computed tomography for contrast agent concentration measurement with monochromatic x-ray beam: comparison of K-edge versus temporal subtraction,

Physics in Medicine and Biology, 47, 3369-3385 (2002)



MC Biston, S. Corde, E. Camus, R. Marti-Battle, F. Estève, J. Balosso

An objective method to measure cell survival by computer-assisted image processing of numeric images of Petri dishes”

Physics in Medicine and Biology 48 1551-1563 (2003)



Monnin P., Bulling S., Hoszowska J., Valley J.F., Meuli R., Verdun F.R.

Quantitative characterization of edge enhancement in phase contrast X-ray imaging

Medical Physics 31, 1372-1383 (2004)



Corde S., Adam JF., Biston MC., Joubert A., Charvet AM., Estève F., Le Bas JF., Elleaume H. Balosso J.

Sensitivity variation of doped Fricke gel irradiated with monochromatic synchrotron X-rays between 33.5 and 80 keV

Radiation Protection Dosimetry (2005), doi:10.1093/rpd/nci313



J Dik, M den Leeuw, K Krug, A Bravin

A New X-ray Method for Painting Studies

Accepted by Zeitschrift fuer Kunsttechnologie und Konservierung, 2005







Elleaume H., Charvet A.M., Berkvens P., Berruyer G., Brochard T., Dabin Y., Dominguez M.C., Draperi A., Fiedler S., Goujon G., Le Duc G., Mattenet M., Nemoz C., Perez M., Renier M., Schulze C., Spanne P., Suortti P., Thomlinson W., Estève F., Bertrand B., Le Bas J.F.


Instrumentation of the ESRF Medical Imaging Facility.


Nucl. Inst. and Meth. A, 428/2-3, 513-527, (1999)




Y. Dabin, A. Draperi, H. Elleaume, A.-M. Charvet, T. Brochard, M. Perez, C. Nemoz, G. Blattmann, M. Renier, F. Fournier, J.-L. Dupuy, B. Lemoine, P. Bouhaniche, W. Thomlinson, P. Suortti,


A patient positioning system for the ESRF medical imaging facility.


Nucl. Inst. and Meth. A 467-468 1342-1345 (2001)




Suortti P, Fiedler S, Bravin A, Brochard T, Mattenet M, Renier M, Spanne P, Thomlinson W, Charvet AM, Elleaume H, Schulze-Briese C, Thompson AC


Fixed-exit monochromator for computed tomography with synchrotron radiation at energies 18-90 keV


Journal of Synchrotron Radiation 7: 340-347 Part 5 2000




Renier M, Brochard T, Nemoz C, Thomlinson W


A white-beam fast-shutter for microbeam radiation therapy at the ESRF


Nucl. Inst. and Meth. A 479 (2-3): 656-660 1 (2002)




A. Bravin, S. Fiedler, P. Coan et al.


Comparison between a position sensitive germanium detector and a taper optics CCD “FRELON” camera for Diffraction Enhanced Imaging


Nucl. Inst. and Meth. A 510 (2003) 35-40




M. Renier, S. Fiedler, C. Nemoz, H. Gonzalez, G. Berruyer, A. Bravin


A mechanical chopper with continuously adjustable duty cycle for a wide X-ray beam


Nucl. Instr. and Methods, A 548 (2005) 111–115


P. Coan, A. Peterzol, S. Fiedler, C. Ponchut, J. C. Labiche and A. Bravin


Evaluation of imaging performance of a taper optics CCD `FReLoN' camera designed for medical imaging


Journal of Synchrotron Radiation (2006) 13, 260-270


C. Nemoz, S. Bayat, G. Berruyer, T. Brochard, P. Coan, G. Le Duc, J. Keyrilainen, S. Monfraix, M. Renier, H. Requardt, A. Bravin, P. Tafforeau, J.F. Adam, MC. Biston, C. Boudou, AM. Charvet, S. Corde, H. Elleaume, F.Estève, A. Joubert, J. Rousseau, I. Tropres, M. Fernandez, L. Porra, P. Suortti, S. Fiedler, W. Thomlinson


Synchrotron Radiation Computed Tomography Station at the ESRF Biomedical Beamline


American Institute of Physics Conference series (2007), Vol. 879, 1887-1890Renier M, Brochard T, Nemoz C, Requardt H, Bräuer E, Esteve F, Balosso J, Suortti P, Baruchel J, Elleaume H, Berruyer G, Berkvens P, Bravin A. “The radiotherapy clinical trials projects at the ESRF: Technical aspects.”
European Journal of Radiology 68S (2008) S147-S150


Olko P., Czopyk L., Klosowski P., Waligórski M.P.R. “Thermoluminescence dosimetry using TL-readers equipped with CCD cameras”
Radiation Measurements 43, 864-869 (2008)

Ptaszkiewicz M., Bräuer-Krisch E., Klosowski M., Czopyk L., Olko P.  “TLD dosimetry for microbeam radiation therapy at the European Synchrotron Radiation Facility”
Radiation Measurements 43, 990-993 (2008)


MicroCT-Paleontology-Material Science




Brunet M., Guy F., Boisserie J.R., Djimdoumalbaye A., Lehmann T., Lihoreau F., Louchart A., Schuster M., Tafforeau P., Likius A., Taisso Mackaye H., Blondel C., Bocherens H., De Bonis L., Coppens Y., Denis C., Duringer P., Eisenmann V., Flisch A., Geraads D., Lopez-Martinez N., Otero O., Pelaez Campomanes P., Pilbeam D., Ponce de Léon M., Vignaud P., Viriot L., Zollikofer C. -


Toumaï ", Miocène supérieur du Tchad, le nouveau doyen du rameau humain


Comptes Rendus Palevol 3, 277-285 (2004)




Michel Brunet, Franck Guy, David Pilbeam, Daniel E. Lieberman, Andossa Likius, Hassane T. Mackaye, Marcia S. Ponce de Leon, Christoph P. E. Zollikofer & Patrick Vignaud


New material of the earliest hominid from the Upper Miocene of Chad"


Nature, Vol 434, pp. 752-755, 7 April 2005


S. Bayat, L. Apostol, E. Boller, T. Brochard, F. Peyrin


In vivo imaging of bone micro-architecture in mice with 3D synchrotron radiation micro-tomography


Nuclear Instruments and Methods in Physics Research A 548 (2005) 247–252


Tafforeau P., Boistel R., Boller E., Bravin A., Brunet M., Chaimanee Y., Cloetens P., Feist M., Hozowska J., Jaeger J.-J., Kay R.F., Lazzari V., Marivaux L., Nel A., Nemoz C., Thibault X., Vignaud P., Zabler S.


Applications of X-ray Synchrotron microtomography for non-destructive 3D studies of paleontological specimens


Applied Physics A 83, 195–202 (2006)




K. Krug, J. Dik, M. den Leeuw, A. Whitson, J. Tortora, P. Coan, C. Nemoz, A. Bravin


K-Edge Imaging of Paintings for Elemental Analysis


Applied Physics A 83, 247–251 (2006)


A. Mazurier, V. Volpato, R. Macchiarelli


Improved noninvasive microstructural analysis of fossil tissues by means of SR-microtomography


Applied Physics A 83, 229–233 (2006)


F. Lihoreau, J.-R. Boisserie, L. Viriot, Y. Coppens, A. Likius, H. Taisso Mackaye, P. Tafforeau, P. Vignaud, and M. Brunet


Anthracothere dental anatomy reveals a late Miocene Chado-Libyan bioprovince


PNAS, Vol. 103 N. 23 June 6, 8763–8767 (2006)




Y. Chaimanee, C. Yamee, P. Tian, K. Khaowiset, B. Marandat, P. Tafforeau, C. Nemoz, and J.-J. Jaeger


Khoratpithecus piriyai, a Late Miocene Hominoid of Thailand


American Journal of Physical Anthropology 131:311–323 (2006)




R. Macchiarelli, L. Bondioli2, A. Debenath, A. Mazurier, J.-F. Tournepiche, W. Birch C. Dean


How Neanderthal molar teeth grew


Nature Vol. 444, 7 Dec., 748-751 (2006)




Paul Tafforeau, Ilhem Bentaleb, Jean-Jacques Jaeger, Céline Martin


Nature of laminations and mineralization in rhinoceros enamel using histology and X-ray synchrotron microtomography: Potential implications for palaeoenvironmental isotopic studies


Palaeogeography, Palaeoclimatology, Palaeoecology xx (2006) xxx–xxx, Accepted 



K Krug, L Porra, P Coan, A Wallert, J Dik, A Coerdt, A Bravin, M Elyyan, P Reischig, L Helfen and T Baumbach


Relics in medieval altarpieces? Combining X-ray tomographic, laminographic and phase-contrast imaging to visualize thin organic objects in paintings


J. Synchrotron Rad. (2008) 15, 55–61




Volpato V., Viola T.B., Nakatsukasa M., Bondioli L., Macchiarelli R. “Textural characteristics of the iliac-femoral trabecular pattern in a bipedally trained Japanese macaque”
Primates 49, 16-25 (2008)

Olejniczak A.J., Smith T.M., Feeney R.N.M., Macchiarelli R., Mazurier A., Bondioli L., Rosas A., Fortea J., de la Rasilla M., Garcia-Tabernero A., Radovcic J., Skinner M.M., Toussaint M., Hublin J.J. - Dental tissue proportions and enamel thickness in Neandertal and modern human molars
Journal of Human Evolution 55, 12-23 (2008)

P. Reischig, J. Blaas, C. Botha, A. Bravin, L. Porra, Ch. Nemoz, A. Wallert and J. Dik “A note on medieval microfabrication: the visualization of a prayer nut by synchrotron-based computer X-ray tomography”
Journal of Synchrotron Radiation Vol. 16,  310-313 (2009)






Thomlinson W, Berkvens P, Berruyer G, Bertrand B, Blattmann H, Brauer E, Brochard T, Charvet AM, Corde S, Di Michiel M, Elleaume H, Estève F, Fiedler S, Laissue JA, Le Bas JF, Le Duc G, Lyubimova N, Nemoz C, Rénier M, Slatkin DN, Spanne P, Suortti P.


Research at the European Synchrotron Radiation Facility Medical Beamline


Cellular and Molecular Biology (2000); 46 (6): 1053-1063



P Suortti and W Thomlinson


Medical applications of synchrotron radiation


Phys. Med. Biol. 48 R1–R35 (2003)



W. Thomlinson, P. Suortti, D. Chapman


Recent advances in synchrotron radiation medical research


Nuclear Instruments and Methods in Physics Research A 543 (2005) 288–296



G Le Duc, P Coan, A Bravin


Biomedical Research at the ESRF: From DNA to Human


Synchrotron Radiation News, 20:3, 25 - 31



Z Bencokova, J Balosso, and N Foray


Radiobiological features of the anti-cancer strategies involving synchrotron X-rays


J. Synchrotron Rad. (2008) 15, 74–85



J. Baruchel, P. Bleuet, S. Bohic, A. Bravin, P. Coan, C. David, H. Elleaume, F. Esteve, F. Peyrin, F. Pfeiffer, P. Suortti, O. Bunk and T. Weitkamp “State of the art and perspectives of biomedical imaging at the ESRF”
Synchrotron Radiation News, 21:4, 30 – 41 (2008)

Baruchel J, Bleuet P, Bravin A, P Coan, E Lima, Anders Madsen, Wolfgang Ludwig, Petra Pernot and Jean Susini “Advances in synchrotron hard X-ray based imaging”
COMPTES RENDUS PHYSIQUE Volume: 9, Issue: 5-6, Pages: 624-641, JUN-AUG 2008



Book chapters


A. Bravin


The biomedical programs at the ID17 beamline of the European Synchrotron Radiation Facility In “Brilliant Light in Life and Material Sciences”, NATO Security through Science Series B; Physics and Biophysics, Edited by V. Tsakanov and H. Wiedemann, Springer The Netherlands, 2007, page 225-239.



Macchiarelli R.,Bondioli L.,Mazurier A. - Virtual dentitions: Touching the hidden evidence
In: “Technique and Application in dental anthropology” Irish J.D.,Nelson G.C. (Eds.) (Cambridge University Press, 2008) pp. 426-448



Other papers of ID17 visiting scientists




Foray, N, Charvet, AM, Duchemin, D, Favaudon, V, and Lavalette, D.,


The repair-rate of radiation-induced DNA damage: A stochastic interpretation based on Gamma function


Journal of Theoretical Biology Oct 21;236(4):448-58, 2005


Marot, D. Opolon, P., Brailly-Tabard, S., Elie, N., Randrianarison, V., Connault, E., Foray, N., Feunteun, J., and Perricaudet, M., 2005,


The tumor suppressor activity induced by adenovirus-mediated BRCA1 overexpression is not restricted to breast cancers


Gene Therapy, 13 (3), 235-244, 2006




Arlett, C.F.Plowman, P.N., Rogers P.B., Parris, C.N., Abbaszadeh, F., Green, M.H.L, McMillan, T.J., Bush, C., Foray, N., Lehmann, A.R.


Clinical and cellular ionising radiation sensitivity in a patient with xeroderma pigmentosum


Br. J. Radiol., in press

De Stasio G, Rajesh D, Ford JM, Daniels MJ, Erhardt RJ, Frazer BH, Tyliszczak T, Gilles MK, Conhaim RL, Howard SP, Fowler JF, Esteve F, Mehta MP


Motexafin-gadolinium taken up in vitro by at least 90% of glioblastoma cell nuclei


Clin Cancer Res. 2006 Jan 1;12(1):206-13



Thomas C. , Fertil B. , Foray N. - Hyperradiosensibilité aux très faibles doses : impact en radiothérapie des micrométastases. Very low-dose hyper-radiosensitivity: Impact for radiotherapy of micrometastases Cancer/Radiothérapie 11, 260-265 (2007)



Gastaldo J., Viau M., Bencokova Z., Joubert A., Charvet A.M., Balosso J., Foray N. ” Lead contamination results in late and slowly repairable DNA double-strand breaks and impacts upon the ATM-dependent signaling pathways”

Toxicology Letters 173, 201-214 (2007)



Varela I, Pereira S, Ugalde AP, Navarro CL, Suárez MF, Cau P, Cadiñanos J, Osorio FG, Foray N, Cobo J, de Carlos F, Lévy N, Freije JM, López-Otín C.

Combined treatment with statins and aminobisphosphonates extends longevity in a mouse model of human premature aging.

Nat Med. 2008 Jul;14(7):767-72. Epub 2008 Jun 29.



Viau M, Gastaldo J, Bencokova Z, Joubert A, Foray N.

Cadmium inhibits non-homologous end-joining and over-activates the MRE11-dependent repair pathway.

Mutat Res. 2008 Jun 30;654(1):13-21. Epub 2008 May



Joubert A, Zimmerman KM, Bencokova Z, Gastaldo J, Chavaudra N, Favaudon V, Arlett CF, Foray N.

DNA double-strand break repair defects in syndromes associated with acute radiation response: at least two different assays to predict intrinsic radiosensitivity?

Int J Radiat Biol. 2008 Feb;84(2):107-25.



Gastaldo J, Viau M, Bouchot M, Joubert A, Charvet AM, Foray N.

Induction and repair rate of DNA damage: a unified model for describing effects of external and internal irradiation and contamination with heavy metals.

J Theor Biol. 2008 Mar 7;251(1):68-81. Epub 2007 Nov 4.



Thomas C, Charrier J, Massart C, Cherel M, Fertil B, Barbet J, Foray N. ”Low-dose hyper-radiosensitivity of progressive and regressive cells isolated from a rat colon tumour: impact of DNA repair.”

Int J Radiat Biol. 2008 Jul;84(7):533-48.



In vivo staining of neocortical astrocytes via the cerebral microcirculation using sulforhodamine B.

Vérant P, Ricard C, Serduc R, Vial JC, van der Sanden B.

J Biomed Opt. 2008 Nov-Dec;13(6):064028.


Corde S. -

Développement méthodologique de l'application d'agents pharmacologiques renforçateurs de l'effet photoélectrique pour l'utilisation du rayonnement synchrotron en radiothérapie anticancéreuse

Thèse présentée devant l'Université Joseph Fourier, Grenoble, France, 2002

Adam J.F. -

Brain tumors and synchrotron radiation: Quantitative brain perfusion imaging and radiation therapy of primary brain tumors (Tumeurs cérébrales et rayonnement synchrotron : développements méthodologiques en imagerie quantitative de la perfusion et en radiothérapie renforcée par effet photoélectrique)

Thèse présentée devant l'Université Joseph Fourier - Grenoble I, France, 2003

Sarnelli A. -

Tecniche a doppia energia in imaging diagnostico : studio di fattibilità per applicazioni in angiografia

Thèse présentée devant l'Université degli Studi di Ferrara, Italy, 2004

Monfraix S. -

Mise au point d'une nouvelle technique d'imagerie fonctionnelle pulmonaire en tomographie quantitative par rayonnement synchrotron

Thèse pour obtenir le titre de Docteur de l'Université Joseph Fourier-Grenoble 1, France, 2004

Rénier W. -

Implication de deux protéines de choc thermique humaines HSO70 et HSP22 dans les voies de la réparation de l'ADN : approche structurale et fonctionnelle

Thèse présentée devant l'Université Joseph Fourier-Grenoble 1, France, 2006

Fernández-Martínez M. - X-ray scattering and diffraction enhanced imaging studies of in vivo breast tissues University of Helsinki (PhD thesis), 20 06

Coan P. -

Development and application of the analyzer-based imaging technique with hard synchrotron radiation

European Synchrotron Radiation Facility and Université Joseph Fourier-Grenoble 1, France, 2006

Boudou C. -

Dosimétrie pour la radiothérapie en rayonnement synchrotron: calculs Monte-Carlo et gels radiosensibles

Thèse présentée devant l'Université Joseph Fourier-Grenoble 1, France, 2006

Erik Albert Siegbahn -

Dosimetry for synchrotron x-ray, microbeam radiation therapy

Technische Universität München October 5th, 2007

Rousseau J. -

Brain tumor chemo-radiotherapy: a study of direct intratumoral perfusion with antineoplasic drugs. (Chimio-radiothérapie des tumeurs cérébrales : intérêt de l'injection intratumorale de drogues antinéoplasiques)

Université Grenoble I - Joseph Fourier, 2007

Régnard P. -

Intérêt du rayonnement synchrotron dans la thérapie des tumeurs cérébrales : méthodologie et applications précliniques

ESRF, Université Grenoble I - Joseph Fourier, 2007

Jenny Spiga, -

Monte Carlo simulation of dose distributions for synchrotron Microbeam Radiation Therapy.

Università degli Studi di Cagliari, Facoltà di Scienze matematiche fisiche e naturali, February 12th, 2008


Other papers of ID17 scientists

Troprès I. , Grimault S. , Vaeth A. , Grillon E. , Julien-Dolbec C. , Payen J.F. , Lamalle L. , Décorps M. - Vessel size imaging
Magnetic Resonance in Medicine 45, 397-408 (2000)


Payen J.F. , Briot E. , Troprès I. , Julien-Dolbec C. , Montigon O. , Décorps M. - Regional cerebral blood volume response to hypocapnia using susceptibility contrast MRI
NMR in Biomedicine 13, 384-391 (2000)

Le Bas J.F. , Kremer S. , Grand S. , Rémy C. , Le Duc G. , Troprès I. , Fonchy E. , Péoc'h M. , Szabo De Edelenyi F. , Estève F. , Rubin C. , Berger F. , Benabid A.L. , Décorps M. - L'imagerie RMN de perfusion : Applications à l'étude de l'angiogenèse tumorale en pathologie cérébrale
Bulletin de l'Académie Nationale de Médecine 184, 23-33 (2000)

Le Duc G. , Vander Elst L. , Colet J.M. , Roch A. , Gillis P. , Le Bas J.F. , Muller R.N. - Ultrasmall particulate iron oxides as contrast agents for magnetic resonance spectroscopy: A dose-effect study
Journal of Magnetic Resonance Imaging 13, 619-626 (2001)