Microsymposium: "Hierarchical imaging of biological, bio-mimetic and bio-compatible materials"

Aim and Scope

Microscopy has been pivotal in advancing our understanding of biological systems ever since the early development of optical microscopy. In recent times, synchrotron-based analytical and imaging techniques have become increasingly powerful for addressing biological problems. These techniques offer clear advances in terms of imaging capabilities, with multi-scale capacity (from cm to nm) and elemental sensitivity. They probe different features of the specimen such as multiple-morphology (phase-contrast imaging), chemical mapping (X-ray fluorescence, Fourier transform infrared spectroscopy, X-ray absorption spectroscopy) and structural contrasts such as diffraction-enhanced imaging (DEI) and coherent diffractive imaging (CDI). In addition, these techniques are suitable for in-situ studies applying a low dose, thus giving access to dynamic processes.

Most biological specimens such as tissues, bones, etc. are composites with a hierarchical structure. Their exceptional properties are believed to be due to functional adaptations of the structure at all levels of hierarchy. Nature has optimized the hierarchical self-assembly over millions of years of evolution to perform the required biological function. A similar strategy is often used to engineer biomimetic and biomaterials to obtain desired functional properties.

Elucidating the hierarchical structure is primordial for deepening our understanding of these systems. Synchrotron-based imaging and scattering methods offer unique possibilities for investigating these systems. This session would offer the opportunity to bring together expert and non-expert users working on a broad range of biological problems and biomaterials using different imaging techniques.

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