Publications RSS feed from the library

Carba-cyclophellitols are neutral retaining-glucosidase inhibitors

Beenakker T.J.M., Wander D.P.A., Offen W.A., Artola M., Raich L., Ferraz M.J., Li K.Y., Houben J.H.P.M., van Rijssel E.R., Hansen T., van der Marel G.A., Codée J.D.C., Aerts J.M.F.G., Rovira C., Davies G.J., Overkleeft H.S.,
Journal of the American Chemical Society 139, 6534-6537 (2017)

A novel non-canonical PIP-box mediates PARG interaction with PCNA

Kaufmann T., Grishkovskaya I., Polyansky A.A., Olek K.M., Kostrhon S., Kukolj E., Olek Karin M., Herbert S., Beltzung E., Mechtler K., Peterbauer T., Gotzmann J., Zhang L., Hartl M., Zagrovic B., Elsayad K., Djinovic-Carugo K., Slade D.,
Nucleic Acids Research 45, 9741-9759 (2017)

De novo active sites for resurrected Precambrian enzymes

Risso V.A., Martínez-Rodríguez S., Candel A.M., Krüger D.M., Pantoja-Uceda D., Ortega-Muñoz M., Santoyo-González F., Gaucher E.A., Kamerlin S.C.L., Bruix M., Gavira J.A., Sánchez-Ruiz J.M.,
Nature Communications 8, 16113-1-16113-13 (2017)

Inward H+ pump xenorhodopsin: Mechanism and alternative optogenetic approach

Shevchenko V., Mager T., Kovalev K., Polovinkin V., Alekseev A., Juettner J., Chizhov I., Bamann C., Vavourakis C., Ghai R., Gushchin I., Borshchevskiy V., Rogachev A., Melnikov I., Popov A., Balandin T., Rodriguez-Valera F., Manstein D.J., Bueldt G., Bamberg E., Gordeliy V.,
Science Advances 3, e1603187-1-e1603187-11 (2017)

Ribosomal antibiotics: Contemporary challenges

Auerbach-Nevo T., Baram D., Bashan A., Belousoff M., Breiner E., Davidovich C., Cimicata G., Eyal Z., Halfon Y., Krupkin M., Matzov D., Metz M., Rufayda M., Peretz M., Pick O., Pyetan E., Rozenberg H., Shalev-Benami M., Wekselman I., Zarivach R., Zimmerman E., Assis N., Bloch J., Israeli H., Kalaora R., Lim L., Sade-Falk O., Shapira T., Taha-Salaime L., Tang H., Yonath A.,
Antibiotics 5, 24-1-24-11 (2016)

8-substituted pyrido[3,4-d]pyrimidin-4(3H)-one derivatives as potent, cell permeable, KDM4 (JMJD2) and KDM5 (JARID1) histone lysine demethylase inhibitors

Bavetsias V., Lanigan R.M., Ruda G.F., Atrash B., McLaughlin M.G., Tumber A., Mok N.Y., Le Bihan Y.V., Dempster S., Boxall K.J., Jeganathan F., Hatch S.B., Savitsky P., Velupillai S., Krojer T., England K.S., Sejberg J., Thai C., Donovan A., Pal A., Scozzafava G., Bennett J.M., Kawamura A., Johansson C., Szykowska A., Gileadi C., Burgess-Brown N.A., von Delft F., Oppermann U., Walters Z., Shipley J., Raynaud F.I., Westaway S.M., Prinjha R.K., Fedorov O., Burke R., Schofield C.J., Westwood I.M., Bountra C., Müller S., van Montfort R.L.M., Brennan P.E., Blagg J.,
Journal of Medicinal Chemistry 59, 1388-1409 (2016)