Overview Programme

---- 17 June
Day 1		 18 June
Day 2		 19 June
Day 3		 20 June
Day 4		 21 June
Day 5		 22 June
Day 6		 23 June
Day 7		 24 June
Day 8
8:00am
to
9:00am		     Safety
Training
Session		          
9:00am
to
10:30am		 Introduction
&
Theory
Session		 Substructures
&
Phasing
Session		 Beamline
Practical
Session		 Substructure
Solution
Session		 Automated
Methods
Session		 Buffer Day Model Building
Session		 Novel Methods
Session
11:00am
to
12:30am		 Introduction
&
Theory
Session		 Substructures
&
Phasing
Session		 Beamline
Practical
Session		 Tutorials
Substructure
Solution		 Tutorials
Automated
Methods		 Buffer Day High
Resolution
Session		 Novel Methods
Session
1:30pm
to
3:30pm		 Introduction
&
Theory
Session		 Experimental Aspects
Session		 Beamline
Practical
Session		 Tutorials
Substructure
Solution		 Tutorials
Automated
Methods		 Buffer Day Beamline
Practical
Session		 Automation
Session
4:00pm
to
6:00pm		 Poster
Presentations
Session		 Experimental Aspects
Session		 Beamline
Practical
Session		 Tutorials
Substructure
Solution		 Tutorials
Automated
Methods		 Buffer Day Beamline
Practical
Session		 Student
Presentations
Session
6:00pm
to
7:00pm		   Burning
Questions
Session		 Special
Topic
Session		 Special
Topic
Session		 Special
Topic
Session		 Buffer Day Special
Topic
Session		 Burning
Questions
Session

 

Detailed Programme

All seminars will be held in the ILL Chadwick Ampitheatre.

Note: Titles are subject to change.

 

Tuesday 17 June 2003

Morning Session: Introduction & Theory (Chair: W. Shepard)

9:00-9:30 Welcome & Introduction to Practical Course R. Ravelli & W. Shepard

9:30-10:00 Challenges in Structural Biology S. Cusack

10:00-10:30 Introduction to 3rd Generation Sources S. Larsen

10:30-11:00 Break

11:00-11:45 Introduction to the Phase Problem in Macromolecular Crystallography E. Dodson

11:45-12:30 Basics of Anomalous Scattering S. McSweeney

12:30-14:00 Lunch in the EMBL-ILL Hallway

Afternoon Session (Chair: M. Walsh)

14:00-14:45 Basics of MAD & SAD Phasing Z. Dauter

14:45-15:30 Historical Introduction to Direct Methods G. Sheldrick

15:30-16:00 Basics of Molecular Replacement R. Read

16:00-16:30 Break

16:30-17:00 The principles of Density Modification E. Dodson

17:00-18:00 Student Poster Presentations Chair: M. Walsh

18:00-19:00 Poster Ice Breaker in EMBL-ILL Hallway

19:00-20:00 Dinner in ESRF Canteen

 

Wednesday 18 June 2003

Morning Session: Substructures, Phasing and Experiments (Chair: G. Leonard)

9:00-9:45  Direct Methods C. Weeks

9:45-10:30 Automated heavy atom location P. Adams

10:30-11:00 Break

11:00-11:45 Maximum Likelihood & Error handling in Phasing G. Bricogne

11:45-12:30 Experimental phasing R. Read

12:30-14:00 Global Phasing Lunch in the EMBL-ILL Hallway

Afternoon Session: Data Collection & Processing (Chair: S. McSweeney)

14:00-14:45 Experimental Considerations W. Shepard

14:45-15:30 Data Collection Strategies Z. Dauter

15:30-15:50 Automated Data Collection & Integration; Mosflm & DNA H. Powell

15:50-16:10 Methods employed by XDS for automatic processing of rotation images W. Kabsch

16:10-16:30 Integration of weak and/or overlapped diffraction patterns with PrOW D. Bourgeois

16:30-17:00 Break

Evening Session: Radiation Damage (Chair: E. Mitchell)

17:00-17:30 Hendersen Limit E. Garman

17:30-17:50 Zero Dose Extrapolation K. Diederichs

17:50-18:10 Temperature-dependent solvent behaviour and radiation damage in proteins M. Weik

18:10-18:30 Radiation-Damage Induced Phasing  R. Ravelli

18:30-18:40 Global Phasing Poster Price

18:40-19:30 Burning Questions Session (Chair: E. Garman)

19:30-20:30 Dinner in ESRF Canteen

 

Thursday 19 June 2003

Morning Session: Safety Training & Beamline Practicals

8:00 Groups 1, 2 & 3 meet at EMBL-ILL Hallway M.J. Villot

8:10-8:30 Safety Training on BM30 for Groups 1, 2 & 3 I. Vernet

8:30 Groups 4, 5 & 6 meet at EMBL-ILL Hallway M.J. Villot

8:40-9:00 Safety Training on BM30 for Groups 4, 5 & 6 I. Vernet

9:00-12:30 Beamline Practicals

  • BM14 ( M. Walsh / H. Belrhali) group 1
  • BM30 ( J.-L. Ferrer / R. Kahn) group 2
  • ID14-EH1 ( D. Hall / I. Leiros) group 3
  • ID14-EH2 ( E. Mitchell / J. McCarthy) group 4
  • ID14-EH4 ( R. Ravelli / A. McCarthy) group 5
  • ID29 ( W. Shepard / P. Legrand / G. Leonard) group 6

12:30-14:00 Lunch at ESRF Canteen

Afternoon Session: Beamline Practicals

14:00-17:30 Beamline Practicals

  • BM14 ( M. Walsh / H. Belrhali) group 5
  • BM30 ( J.-L. Ferrer / R. Kahn) group 6
  • ID14-EH1 ( D. Hall / I. Leiros) group 1
  • ID14-EH2 ( E. Mitchell / J. McCarthy) group 2
  • ID14-EH4 ( R. Ravelli / A. McCarthy) group 3
  • ID29 ( W. Shepard / P. Legrand / G. Leonard) group 4

18:00-19:00 The Theoretical Basis of the Joint Probability Distribution Functions for SIR-MIR,SIRAS-MIRAS,SAD-MAD C. Giacovazzo

19:00-20:00 Dinner in ESRF Canteen

 

Friday 20 June 2003

Morning Session: Substructure Solution & Tutorials (Chair: J.L. Ferrer)

9:00-9:30 SnB & BnP C. Weeks

9:30-10:00 Substructure Solution with SHELXD G. Sheldrick

10:00-10:30 PHENIX: new software for automated structure determination P. Adams

10:30-11:00 Break

11:00-12:30 Tutorials

  • SnB & BnP ( C. Weeks) groups 1 & 2 in EMBL Graphics Room
  • SHELXD/E ( G. Sheldrick / G. Bunkoczi) groups 3 & 4 in ESRF Graphics Room
  • CNS ( P. Adams/ R. Read) groups 5 & 6 in EMBL Seminar Room

12:30-14:00 Lunch at ESRF Canteen

Afternoon Session: Tutorials

14:00-15:30 Tutorials

  • SnB & BnP ( C. Weeks) groups 5 & 6 in EMBL Graphics Room
  • SHELXD/E ( G. Sheldrick / G. Bunkoczi) groups 1 & 2 in ESRF Graphics Room
  • CNS ( P. Adams / R. Read) groups 3 & 4 in EMBL Seminar Room

15:30-16:00 Break

16:00-17:30 Tutorials

  • SnB & BnP ( C. Weeks) groups 3 & 4 in EMBL Graphics Room
  • SHELXD/E ( G. Sheldrick / G. Bunkoczi) groups 5 & 6 in ESRF Graphics Room
  • CNS ( P. Adams / R. Read) groups 1 & 2 in EMBL Seminar Room

18:00-19:00 Special Topic: Medical Beamline G. LeDuc

19:30-22:00 Dinner in Restaurant 

 

Saturday 21 June 2003

Morning Session: Automatic Phasing & Tutorials (Chair: R. Ravelli)

9:00-9:45 SOLVE Li-Wei Hung

9:45-10:30 AutoSHARP G. Evans

10:30-11:00 Break

11:00-12:30 Tutorials

  • Open Session groups 1 & 2 in EMBL Graphics Room
  • SOLVE ( Li-Wei Hung) groups 3 & 4 in ESRF Graphics Room
  • autoSHARP ( G. Evans / G. Bricogne) groups 5 & 6 in EMBL Seminar Room

12:30-14:00 Lunch at ESRF Canteen

Afternoon Session: Tutorials

14:00-15:30 Tutorials

  • Open Session groups 5 & 6 in EMBL Graphics Room
  • SOLVE ( Li-Wei Hung) groups 1 & 2 in ESRF Graphics Room
  • autoSHARP ( G. Evans / G. Bricogne) groups 3 & 4 in EMBL Seminar Room

15:30-16:00 Break

16:00-17:30 Tutorials

  • Open Session groups 3 & 4 in EMBL Graphics Room
  • SOLVE ( Li-Wei Hung) groups 5 & 6 in ESRF Graphics Room
  • autoSHARP ( G. Evans / G. Bricogne)  groups 1 & 2 in EMBL Seminar Room

18:00-19:00 Special Topic: Phasing from SAXS Envelopes Q. Hao

19:00-20:00 Dinner in ESRF Canteen

20:00 Fete de la Musique

 

 

Sunday 22 June 2003

Buffer Day

12:00-13:00 Lunch at ESRF Canteen

13:00-23:30 Excursion Chartreuse & Banquet at the Auberge de Sarcenas

 

Monday 23 June 2003

Morning Session: Model Building & High Resolution (Chair: G. Leonard)

9:00-9:45 ARPwARP A. Perrakis

9:45-10:30 Model Building using RESOLVE Li-Wei Hung

10:30-11:00 High Throughput Phasing with SHELXE G. Sheldrick

11:00-11:30 Break

11:30-12:00 Applications of the JPDF method to SIR-MIR,SIRAS-MIRAS,SAD-MAD cases. Ab initio techniques C. Giacovazzo

12:00-12:30 Ultra-high Resolution studies on Aldose Reductase A. Podjarny

12:30-14:00 Lunch in the EMBL-ILL Hallway

Afternoon Session: Beamline Practicals

14:00-18:30 Beamline Practicals & Autobuilding tutorials

  • BM14 ( M. Walsh / H. Belrhali) group 3
  • BM30 ( J.-L. Ferrer / R. Kahn) group 4
  • ID14-EH1 ( I. Leiros) group 5
  • ID14-EH2 ( E. Mitchell / J. McCarthy) group 6
  • ID14-EH4 ( R. Ravelli / A. McCarthy) group 1
  • ID29 ( W. Shepard / P. Legrand / G. Leonard) group 2

18:30-19:00 Special Topic: Micro X-ray beams for Biology C. Riekel/M. Burghammer/M. Roessle

19:00-20:00 Dinner in ESRF Canteen

 

Tuesday 24 June 2003

Morning Session: Long X-ray Wavelengths (Chair: W. Shepard)

9:00-9:35 Ultra-long X-ray wavelengths  H. Stuhrmann

9:35-10:10 Phosphor Phasing Z. Dauter

10:10-10:30 Sulphur Phasing E. Micossi

10:30-11:00 Break

Morning Session: Medium & Short X-ray Wavelengths (Chair: A. McCarthy)

11:00-11:20 Remote SAD G. Leonard

11:20-11:40 Iodine Phasing G. Evans

11:40-12:00 Novel Heavy Atom Compounds M. Stelter

12:00-12:30 Ultra-short X-ray Wavelengths P. Tucker

12:30-14:00 Lunch in the EMBL-ILL Hallway

Afternoon Session: Automation (Chair: E. Mitchell)

14:00-14:20 Automation on BM30 J.L. Ferrer

14:20-14:40 Sample Changer & Microdiffractometer F. Cipriani

14:40-15:00 Auto Edge Scans W. Shepard

15:00-15:20 ABA and DNA, O. Svensson

15:20-15:40 Automation of MX D. Nurizzo

15:40-16:30 Break & Student Presentation Preparations

16:30-17:30 Student Presentations Chair: S. McSweeney

17:30-19:00 Round Table discussion & Burning Questions Chair: Z. Dauter

19:00-20:00 Dinner in ESRF Canteen