ID23-1: Gemini - Macromolecular Crystallography

Synopsis

ID23-1 offers the opportunity to make highly efficient monochromatic measurements at energies from 5 Kev to 20 Kev with a flux of ~1-4 E12 photons/second and a variable beam size from 0.05 to 0.001 mm^2.
Status:  open

Disciplines

  • Life Sciences

Applications

  • Life science

Techniques

  • MX - macromolecular crystallography
  • MAD - multi-wavelength anomalous dispersion

Energy range

  • 5.0 - 20.0  keV

Beam size

  • Minimum (H x V) : 10.0 x 10.0  µm²
  • Maximum (H x V) : 45.0 x 30.0  µm²

Sample environments

  • Low temperature (70 K)

Detectors

  • ADSC Q315R detector, active area of 315 x 315 mm2 (3072 x 3072 pixels, which are 102.6 microns in size for the default binned mode). The readout time is 1 second (unbinned mode) or 0.3 second (binned mode)
  • X-ray fluorescence detector - Rontec Silicon drift diode (energy resolution 250 eV at 5.9 keV and a maximum count rate of 1 MHz)

Didier Nurizzo, Trevor Mairs, Matias Guijarro, Vicente Rey, Jens Meyer, Pablo Fajardo, Joel Chavanne, Jean Claude Biasci, Sean McSweeney and Edward Mitchell, "The ID23-1 structural biology beamline at the ESRF", J. Synchrotron Rad. 13(Pt 3) (2006) 227-38.

Latest publications

View all publications
Carba-cyclophellitols are neutral retaining-glucosidase inhibitors

Beenakker T.J.M., Wander D.P.A., Offen W.A., Artola M., Raich L., Ferraz M.J., Li K.Y., Houben J.H.P.M., van Rijssel E.R., Hansen T., van der Marel G.A., Codee J.D.C., Aerts J.M.F.G., Rovira C., Davies G.J., Overkleeft H.S.,
Journal of the American Chemical Society 139, 6534-6537 (2017)